Hepatitis C
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Materials presented have not been evaluated by the U.S. Food & Drug Administration and are not meant as a replacement or substitute for professional medical diagnosis and treatment. Visitors are advised to seek professional medical care for any any disease or illness.
 


 

 

Articles by
Dr. Zhang
 
TCM and MCM Theory Related to Common Liver Disease Blood Test Markers

Low Dose Interferon Patient Experiment

Hepatitis A Prevention Reminder

Hepatitis: Causes of Pain in Liver Region 

The Need to Monitor Your Chronic Hepatitis

Liver Enzyme Fluctuation during Allergy Season 

What are the Serum Markers of Hepatitis B and What do They Mean?

Enterogenous Endotoxemia in Chronic Hepatitis–
Part 2

Enterogenous Endotoxemia in Chronic Hepatitis–
Part 1
 

Chronic Hepatitis and "Blood Activating and Stasis Expelling" (BASE) Therapy -
Part 2

Chronic Hepatitis and "Blood Activating and Stasis Expelling" (BASE) Therapy
Part 1

What Causes Gastrointestinal Bleeding in Cirrhotic Liver Disease

Dietary Support for Cirrhotic Liver Diseases

Ascites - A Complication of De-Compensated Liver Cirrhosis

Liver Cirrhosis - Portal Vein Hypertension Complications

Liver Cirrhosis Overview

PG-IFN and Ribavirin Treatments

Antibiotics and Chronic Liver Diseases

Why is Alcohol Harmful for People with Hepatitis?

Co-infections and Super-infections of Viral Hepatitis

Beware of Medications That Can Cause Liver Damage

Bile Retention and Its Clinical Manifestations (MCM) part 4

Modern Chinese Medicine (MCM) Part 3 
Jaundice and Chronic Viral Hepatitis

Modern Chinese Medicine (MCM) Anti-Liver-Fibrosis Treatments - Part 2

Modern Chinese Medicine (MCM) Anti-Liver-Fibrosis Treatments - Part 1

What is Liver Fibrosis and How is It Different from Cirrhosis?

How does the liver change as we get older?

How is that my LFTs are so good when my viral load is seemly so high?

Comprehensive Care for Chronic Viral Hepatitis

What can Cause Liver Inflammation?  

What Are the Major Functions that the Liver Carries?


 

Liver Support with TCM
GGT
This information is for educational purposes only.
Materials regarding herbs have not been evaluated by the
U.S. Food & Drug Administration and are not in any way a replacement or substitute for professional medical diagnosis and treatment. Persons with specific medical illnesses are advised to seek professional care.

Liver cells synthesize GGT and serum GGT mainly originates from the liver. Under the stimulation of inflammation, bile retention, or cancer, the synthesis of GGT in liver cells will increase. Clinically, its significance is similar to that of ALP, but even more sensitive. GGT elevation could be seen in about 90% of chronic liver and gall bladder disease patients. It is especially obvious in bile retention and cancer patients. In early stages of acute hepatitis, mild chronic hepatitis, and inactive cirrhosis, GGT is usually not elevated. At the peak stage of the acute hepatitis, pre-cirrhotic chronic hepatitis, fatty liver, kidney damage, pancreatitis, diabetes, and heart muscle injuries, GGT it may increase to one to two times above the normal range.

In following conditions, GGT could elevate to two to four times above the normal range: chronic moderate to severe hepatitis, active cirrhosis, alcoholic hepatitis and fatty liver, acute pancreatitis, acute blood stasis in the liver, localized liver cancer damage, acute cardio infarction, and incomplete stenosis of bile ducts.

In following conditions, it could elevate to five to ten times or higher than the normal range: intra liver bile retention, biliary cirrhosis, and liver cancer.

Although GGT is sensitive, it is not as specific as ALP. Thus, testing with ALP together offers a more complete assessment. When GGT is elevated and ALP is normal, it may be a toxin related. Toxins include alcohol and a number of medications including anti-seizure medications, Coumadin. If both GGT and ALP are elevated, extra-hepatic bile duct stenosis may be the underlying cause.

GGT elevation should also be evaluated together with ALT. If there is slight elevation of both, liver damage is probably light. The severity of the GGT elevation is directly correlated to liver damage.

When GGT is elevated in cases of acute hepatitis or moderate liver disorders, besides using “heat clearing and toxin dissolving” and “heat clearing and dampness eliminating” anti-inflammation herbal treatments, some “blood activating and stasis expelling” herbs should be added:
Dan Shen (Salviae Miltiorrhziae Radix), Qing Pi (Citri Immaturi Pericarpium)
Chen Pi (Citri Pericarpium), Ze Lan (Lycopi herba)
Yin Xin Ye (Ginkgo biloba herba).

If there is obvious bile duct stenosis, then following “Li dan tong chang” (normalizing the secretion and discharge of bile) and “Po xue qu yu” (removing blood stasis) herbs should be used:
San Leng (Sparganii Rhizoma)
E Zhu (Zedoariae Rhizoma)
Bie Jia (Amydae Flos)
Da Huang (Rhei Rhizoma)
Dan Shen (Salviae Miltiorrhziae Radix)
Ji Xue Teng (Mucunae Caulis)
Shui Zhi (Hirudo nipponica, Leech).

These herbs should be used together with “heat clearing and toxin dissolving” and “heat and jaundice clearing” herbs.

In summery, GGT elevation is an indication of blood stasis in TCM. Whenever there is elevation of GGT, “blood activation and stasis expelling” herbs should be used in the formulation of the herbal remedies.

[Liu YL et al., Premary Discusion on the Use of Chinese Medicine According to Blood Tests, CJITWM, Jan 2003, 23(1):54-55]

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About HCV
Overview
Causes and Transmission

 
Diagnostic Tests
Antibody
HCV RIBA
HCV RNA 
Viral Load

Viral Genotyping

 
Major Signs
Liver Inflammation
Fibrosis
Cirrhosis

 
Peripheral Signs and Symptoms
Fatigue
Jaundice
Bile Retention
Joint Pains and Skin Rashes
Blood Sugar Instability
Portal Vein Hypertension
Ascites

 
Important Liver Function Test Markers
Overview
ALT and AST
ALP and GGT
Albumin
Bilirubin
PT (Prothrombin Time)
 
Liver Biopsy
Overview
Procedure
Inflammation Grade
Fibrosis Stage
 
Interferon Based Treatment
Overview
Ideal Candidate
Possible Side-effects
 
Liver Support with TCM
Overview
Liver Enzymes
Serum Albumin
Blood Clotting Factors
Bile metabolism
GGT
 
Dietary Considerations
Overview
Proteins
Essential Fats
Carbohydrates
Vitamins
 
 

 


 

 

Medical Information Sources:
http://www.nih.gov/
http://www.nlm.nih.gov/

http://nccam.nih.gov/
http://www.medlineplus.org/


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