Enterogenous Endotoxemia in Chronic Hepatitis – Part 2

Prevention and Treatment of EE With Modern Chinese Medicine

To prevent and treat EE, the first important thing is to actively treat the underlying liver inflammation, reduce the hypertension of the portal vein, and reverse liver fibrosis. Once liver functions are improved, the factors promoting EE will also be gradually eliminated.

Symptomatic treatments are also important in reducing the production of intestinal endotoxin (IE).  Treating constipation and regulating bowel movement can effectively reduce the production of IE and for this, we use the Rhubarbin Tablet or formula # 733 (Rhubarb and Mirabilitum Combination) to adjust the bowel movements to two to three times a day and slightly loosen the stool. This treatment can reduce the amount of time that the stool remains in the colon and reduce the production and absorption of IE. In addition, using colonotherapy to eliminate stagnant stool in the colon can also reduce IE production. Anti-bacterial herbs, can dramatically suppress the overgrowth of bacterial flora and thus reduce IE production. Because the high potency of these herbs can suppress healthy bacterial flora, weekly breaks are recommended and during the break, acidophilus and yogurt can be used to re-establish the growth of healthy bacteria.

If EE has already been developed, treatment should focus on resolving the EE pathology and detoxify the IE. In China, many single herbs and their active ingredients have been studied and proven to be effective treatments for EE. These include: Chuan Xiong (Cnidii Rhizoma), Dan Shen (Salviae Miltiorrhziae Radix), Huang Qi (Astragali Radix), Ren Shen (Ginseng Radix), have been found to de-activate the IE. Pu Gong Ying (Taraxaci Herba), Ban Lan Gen (Isatidis Radix), Jin Yin Hua (Lonicerae Flos), and Shan Dou Gen (Sophorae Subprostratae Radix) can decompose the IE.  Da Huang (Rhei Rhizoma), Huang Lian (Coptis chinensis Franch), Huang Qin (Scutellariae Radix), Zhi Zi (Gardeniae Fructus), and Dan Shen (Salviae Miltiorrhziae Radix), can reduce the production of the IE in the intestine.