|
Fibrosis usually begins
in the portal area in HCV and in the central vein in alcoholic liver
disease. Bridging fibrosis refers to the presence of fibrosis that
reaches from a portal area to another portal area. Cirrhosis consists of
extensive bridging fibrosis in the presence of regeneration such that
normal portal areas and normal central veins cannot be identified.
|
0 |
No fibrosis |
Normal
connective tissue |
|
1 |
Portal
fibrosis |
Fibrous
portal expansion |
|
2 |
Periportal
fibrosis |
Periportal
or rare portal-portal septa |
|
3 |
Septal
fibrosis |
Fibrous
septa with architectural distortion; no obvious
cirrhosis |
|
4 |
Cirrhosis |
Cirrhosis |
|
|
