Clinical Features of Alcoholic Hepatitis In the early stage of this disease, there may not be any noticeable symptoms. However, the pathological changes are already occurring and the onset of the disease is usually triggered by a one-time large consumption of alcohol. The most common symptoms include weight loss, poor appetite, nausea, vomiting, fatigue, fever, stomach discomfort, and diarrhea. In some cases, upper gastrointestinal bleeding and psychological symptoms will also develop. The physical signs include jaundice, enlarged liver and spleen, tenderness in the liver area, grayish complexion, edema, spider moles, and varices in the esophagus. Laboratory tests may indicate anemia, increase of neutrocytophilia ( a kind of WBC), MCV> 95FL, increase of bilirubin level, moderate ALT and AST elevation, GGT and AKP elevation, and prolonged PT and PTT. If a long-term drinker starts to show these symptoms, he or she should stop drinking immediately and seek medical care.