Is Fibrosis reversible?

If this pathological process can be held, or reversed, the prognosis of chronic liver disease can be greatly changed. Through many years of studies in animal cirrhotic models, it has been proven that reversal fibrosis is possible, even in the early stages of liver cirrhosis. The question is, at what stage does fibrosis become irreversible? In order to study this problem, we are badly in need of a non-invasive method to assess the progression of fibrosis and how anti-fibrosis treatment is working. Although many researchers found that fibrosis is reversible, it was a common brief that cirrhosis is irreversible. Some clinical researches done in China found recently that cirrhosis, especially its early stage can be reversed, which challenges this common brief.

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